Sclerosing adenosis

Cancerisation of lobules - Smooth muscle actin

Cancerisation of lobules (Smooth muscle myosin heavy chain)

Calponin

Microinvasion (p63)

High grade DCIS (Cytokeratin 5)

Microinvasion (Smooth muscle actin - high power)

Microinvasion (p63)

Microinvasion (Cytokeratin 5)

Adenoid cystic carcinoma (Haematoxylin and Eosin)

High grade DCIS (p63 discontinuity)